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True Accutane contains isotretinoin, a stereoisomer of all-transretinoic acid (tretinoin). The exact mechanism of action of Accutane has not yet been clarified, but it has been established that the improvement in the clinical picture of severe forms of acne is associated with the suppression of the activity of the sebaceous glands and a histologically confirmed decrease in their size. In addition, the anti-inflammatory effect of isotretinoin on the skin has been proven.

Hyperkeratosis of epithelial cells of the hair follicle and sebaceous gland leads to desquamation of corneocytes into the duct of the gland and to blockage of the latter with keratin and excess sebaceous secretion. This is followed by the formation of a comedone and, in some cases, the addition of an inflammatory process.

Accutane suppresses the proliferation of sebocytes and acts on acne by restoring the normal process of cell differentiation. Sebum is the main substrate for the growth of Propionibacterium acnes, therefore, reducing sebum production inhibits bacterial colonization of the duct. Before thinking about where I can buy cheap Accutane online, read the instructions and consult a master doctor.

Instructions for use

The therapeutic efficacy of Accutane and its side effects are dose dependent and vary from patient to patient. This dictates the need for individual dose selection during treatment.

Accutane treatment should be started at 0.5 mg / kg / day. In most patients, the dose ranges from 0.5 to 1 mg / kg of body weight per day. Patients with very severe forms of the disease or with acne in the trunk area may require higher daily doses – up to 2 mg / kg. It has been proven that the frequency of remission and prevention of relapses are optimal when using a course dose of 120–150 mg / kg (per course of treatment), therefore the duration of therapy in specific patients varies depending on the daily dose. Complete remission of acne is often achieved within 16-24 weeks of treatment.

Indications:

  • Severe acne (multiple, suppurating, sclerosing, group acne).

Contraindications:

  • The period of pregnancy;
  • Lactation period;
  • Hepatic dysfunction;
  • Excess vitamin A;
  • High blood cholesterol levels;
  • Taking antibiotics of the tetracycline series;
  • Intolerance to the drug or its components;
  • Children under 12 years of age.

Before starting therapy with this drug, every woman must undergo a pregnancy test to prevent harm to herself or the unborn child, duly instructed about the consequences for the fetus in case of an unplanned pregnancy while taking the drug and within three months after its termination.

Isotretinoin has the strongest teratogenic effect on the fetus (in any concentration, including with a single dose), causing the most severe malformations at any stage of pregnancy, therefore it cannot be indicated for use in pregnant women.

Where to buy Accutane

You can buy Accutane online by visiting pharmacy websites. The drug is now available in almost all online pharmacies. It is likely that you may be asked to provide a doctor’s prescription for the use of the medicine, even if you decide to buy a generic Accutane – the medicine can greatly harm the woman’s body and the unborn child.

Cheap Accutane can be found under these names:

  • Roaccutane;
  • Acnecurane;
  • Sotret;
  • Retinoic ointment;
  • Uroderm.

Finding a cheap Accutane online is very easy. To do this, look in pharmacies not for a specific trade name, but for the active ingredient isotretionin itself.